ID 原文 译文
1007 根据炎症损伤程度，甲泼尼龙琥珀酸钠（甲强龙）常规起始剂量每天0.75~1.5mg/kg分1~2次静脉注射；对于常规剂量不能控制体温，或者细胞因子仍然显著升高的重症患者可以考虑40mg q12h，危重症患者可以使用40mg-80mg q12h。 Initial routine methylprednisolone at a dose of 0.75~1.5 mg/kg intravenously once a day (nearly 40 mg once or twice a day) is recommended. However, methylprednisolone at a dose of 40 mg q12h can be considered for patients with falling body temperature or for patients with significantly increased cytokines under routine doses of steroid. Even methylprednisolone at a dose of 40 mg-80 mg q12h can be considered for critical cases.
1008 治疗期间，密切监测体温、血氧饱和度，每隔2~3d复查血常规、C反应蛋白、细胞因子、生化指标、血糖、肺部CT等评估病情及疗效。 Closely monitor body temperature, blood oxygen saturation, blood routine, C-reactive protein, cytokines, biochemical profile and lung CT every 2 to 3 days during the treatment as necessary.
1009 如病情改善，体温正常，或肺部影像有吸收，则每3~5d激素减半，减至每日20mg/d后序贯甲泼尼龙（美卓乐）口服,根据病情确定疗程。 The dosage of methylprednisolone should be halved every 3 to 5 days if medical conditions of patients are improved, the body temperature normalizes, or involved lesions on CT are significantly absorbed. Oral methylprednisolone (Medrol) once a day is recommended when the intravenous dose is reduced to 20 mg per day. The course of corticosteroids in not defined; some expert s have suggesting ceasing corticosteroids treatment when patients are nearly recovered.
1010 1.3治疗期间注意事项 1.3 Special Consideration during Treatment
1011 ①治疗前完善结核菌感染T细胞斑点（T-SPOT）试验、乙型肝炎病毒和丙型肝炎病毒标志物等检测，避免在激素治疗过程中激活潜在感染； ① screening of TB by T-SPOT assay, HBV and HCV by antibody assay should be performed before corticosteroid therapy;
1012 ②根据情况应用质子泵抑制剂、钙剂预防并发症； ② proton pump inhibitors could be considered to prevent complications;
1013 ③监测血糖，一旦出现血糖升高，皮下注射胰岛素控制血糖； ③ blood glucose should be monitored. High blood glucose should be treated with insulin when necessary;
1014 ④监测血钾，纠正低钾血症； ④ low serum potassium should be corrected;
1015 ⑤监测肝功能，及时进行护肝治疗； ⑤ liver function should be monitored closely;
1016 ⑥出现多汗、自汗者，可试用中药； ⑥ traditional Chinese herbal medicine may be considered for patients who are sweating;