ID 原文 译文
1247 进行血药浓度监测 Therapeutic Drug Monitoring
1248 需要治疗药物监测(therapeutic drugmonitoring,TDM)的抗病毒和抗菌药物血药 Some antiviral and antibacterial drugs need therapeutic drug monitoring (TDM).
1249 浓度与剂量调整见表1,一旦发现血药浓度异常,应结合患者临床症状、合并用药,进行方案调整,实行个体化给药。 Table 1 presents the plasma concentrations of such drugs and their dosage adjustment. Upon the onset of aberrations of plasma drug concentration, the treatment regimens need to be adjusted by considering the clinical symptoms and concomitant drugs.
1250 表1 COVID-19患者常见TDM药物的浓度范围及注意事项 Table 1 The range of concentrations and points for attention of the common TDM drugs for the COVID-19 patients
1251 药品名称 Drug names
1252 采血时间点 Time points of blood collection
1253 治疗浓度范围 剂量调整原则 The range of concentrations Principles of dosage adjustment
1255 (峰)给药后30min内 (peak) 30 min after drug administration
1256 (谷)给药前30min内 (trough) 30 min before drug administration
1257 洛匹那韦:(谷)>1μg/mL(峰)<8.2μg/mL lopinavir: (trough)> 1 μg/mL (peak) < 8.2 μg/mL