ID |
原文 |
译文 |
1296 |
③与吡嗪酰胺联合使用可使血液中尿酸水平升高;
|
Its combination with pyrazinamide increases the plasma uric acid level.
|
1297 |
④与瑞格列奈联合使用会导致瑞格列奈血药浓度升高。
|
Its combination with repaglinide increases the plasma repaglinide level.
|
1299 |
严禁与莫西沙星、阿奇霉素、胺碘酮等可能导致Q-T间期延长的药物合用。
|
Prohibit to combine with the drugs that may lead to the prolonged Q-T interval (such as moxifloxacin, azithromycin, amiodarone, etc.).
|
1300 |
注:“—”无相关资料;TDM:治疗药物监测;AUC:药时曲线下面积;
|
Note:“—”: no relevant data;TDM:therapeutic drug monitoring;AUC:area under the curve;
|
1301 |
UGT1A9:尿苷二磷酸葡萄糖苷酸基转移酶1A9
|
UGT1A9:uridine diphosphate glucosidase 1A9.
|
1302 |
特殊人群避免用药损伤
|
Avoiding medical damage in special populations
|
1303 |
特殊人群包括孕妇、肝肾功能不全,机械通气、连续肾脏替代治疗(Continuousrenal replacement therapy, CRRT)、体外膜肺氧合治疗(Extracorporeal membrane oxygenation,ECMO)等患者 |
Special populations include pregnant women, patients with hepatic and renal insufficiency, patients supported by mechanical ventilation, patients under continuous renal Replacement therapy (CRRT) or, extracorporeal membrane oxygenation (ECMO), etc. |
1304 |
在给药过程中注意以下事项:
|
The following aspect s need to be noted during drug administration.
|
1305 |
1)孕妇患者,可选用洛匹那韦/利托那韦,禁用法匹拉韦、磷酸氯喹等;
|
(1) Pregnant women
Lopinavir/ritonavir tablets could be used. Favipiravir and chloroquine phosphate are prohibited.
|
1306 |
2)肝功能不全患者,尽量选择原形经肾脏排泄的药物,比青霉素类、头孢菌素类等;
|
(2) Patients with hepatic insufficiency Drugs that are excreted unchanged through the kidney are preferred, such as penicillin and cephalosporins, etc.
|