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49790 然而，研究的评价工作需要有充足的人力、随机、对照试验以及符合实际的、科学的操作标准以及适当的患者分层。 However, evaluation of investigational agents requires adequately powered, randomized, controlled trials with realistic eligibility criteria and appropriate stratification of patients.
49791 中国与其他地区开展相应的合作研究同样重要。 It is important for there to be a degree of coordination between those conducting studies within and beyond China.
49792 开发安全有效的呼吸道病毒疫苗是防治该病的重要手段。 The development of a safe and effective vaccine for this highly communicable respiratory virus is an important epidemic control measure.
49793 重组蛋白、mRNA、DNA、灭活全病毒和重组腺病毒疫苗目前正在研制中，一些疫苗巳进入动物实验阶段。 Recombinant protein, mRNA, DNA, inactivated whole virus and recombinant adenovirus vaccines are being developed and some are now entering animal studies.
49794 鉴于以往曾有灭活全病毒麻疹疫苗导致疾病严重效应以及SARS样冠状病毒疫苗在动物实验的类似报道，疫苗的安全性是冠状病毒感染研究的首要考虑。 Vaccine safety is of prime concern in the area of coronavirus infection in view of the past experience of disease enhancement by inactivated whole virus measles vaccine and similar reports in animal experiments with SARS coronavirus vaccines.
49795 这些候选疫苗快速进入适当的临床试验也尤为重要。 It will be important that these vaccine candidates rapidly move into appropriate clinical trials.
49796 研究病毒传播途径、发病机制、抗病毒治疗、疫苗和免疫应答的理想动物模型尚未找到。 The ideal animal model for studying routes of virus transmission, pathogenesis, antiviral therapy, vaccine and immune responses has yet to be found.
49797 转人ACE2基因小鼠模型和恒河猴模型巳在实验室中得到应用。 The ACE2 transgenic mouse model and Macaca Rhesus model are already used in research laboratories.
49798 系统地阐述哪些动物模型能够更加准确地模拟人类感染尤为重要。 Systematically addressing which models can accurately mimic human infection is required.
49799 口罩、手部卫生用品和其他个人防护用品在全球的需求量激增。 There is a global rush for masks, hand hygiene products and other personal protective equipment.