ID |
原文 |
译文 |
917 |
病毒滴度测定:将病毒原液按10倍系列稀释后,采用微量细胞病变法测定TCID50,或采用蚀斑试验计数蚀斑形成单位(plaque forming unit,PFU)测定病毒感染活力。 |
Virus titer measurement: After diluting the virus stock concentration by a factor of 10 in series, the TCID50 is determined by the micro-cytopathic method. Otherwise, viral viability is determined by plaque forming unit (PFU).
|
918 |
血清抗体检测
|
Detection of Serum Antibody
|
919 |
SARS-CoV-2感染后会产生特异性抗体。 |
Specific antibodies are produced after SARS-CoV-2 infection. |
920 |
血清抗体测定方法有:胶体金免疫层析法、ELISA、化学发光免疫分析等。患者血清特异性IgM阳性,或恢复期特异性IgG抗体滴度较急性期升高4倍及以上,可作为核酸检测阴性疑似患者的诊断依据。 |
Serum antibody determination methods include colloidal gold immunochromatography, ELISA, chemiluminescence immunoassay, etc. Positive serum-specific IgM, or specific IgG antibody titer in the recover y phase ≥4 times higher than that in the acute phase, can be used as diagnostic criteria for suspected patients with negative nucleic acid detection. |
921 |
通过随访监测,发现在患者发病后10天可检出IgM,发病后12天检出IgG,并随着血清抗体水平升高,病毒核酸载量逐渐下降。
|
During follow-up monitoring, IgM is detectable 10 days after symptom onset and IgG is detectable 12 days after symptom onset. The viral load gradually decreases with the increase of serum antibody levels.
|
922 |
炎症反应指标的检测
|
Detecting Indicators of Inflammatory Response
|
923 |
建议开展C反应蛋白、降钙素原、铁蛋白、D-二聚体、淋巴细胞总数及亚群、IL-4、IL-6、IL-10、TNF-α、INF-γ等反应机体炎症与免疫状态的检查,有助于判断临床进程,预警重症、危重症倾向,并为治疗策略制订提供依据。
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It is recommended to conduct test s of C-reactive protein, procalcitonin, ferritin, D-dimer, total and subpopulations of lymphocytes, IL-4, IL-6, IL-10, TNF-α, INF-γ and other indicators of inflammation and immune status, which can help evaluate clinical progress, alert severe and critical tendencies, and provide a basis for the formulation of treatment strategies.
|
924 |
大多数新冠肺炎患者降钙素原正常,C反应蛋白显著升高,C反应蛋白迅速大幅升高提示可能出现继发感染。 |
Most patients with COVID-19 have a normal level of procalcitonin with significantly increased level s of C-reactive protein. A rapid and significantly elevated C-reactive protein level indicates a possibility of secondary infection. |
925 |
重症患者D-二聚体水平显著升高,是患者预后不良的潜在危险因素。 |
D-dimer level s are significantly elevated in severe cases, which is a potential risk factor for poor prognosis.
|
926 |
发病初期淋巴细胞总数较低的患者一般预后较差,且重症患者外周血淋巴细胞数量呈进行性减少。
|
Patients with a low total number of lymphocytes at the beginning of the disease generally have a poor prognosis. Severe patients have a progressively decreased number of peripheral blood lymphocytes. |